The Centers for Disease Control and Prevention (CDC) has released its first blueprint of a four-pronged ethical basis which will determine how the coronavirus vaccine could be released to reach more than 261 million people who fall into the category of essential workers. A high-powered Advisory Committee on Immunisation Practices responsible for making vaccine recommendations while supply is limited laid out four principles that will guide allocation: Maximise benefits and minimise harms; Promote justice; Mitigate health inequities; Promote transparency. The current planning scenario estimates that in the first weeks spanning December and January, only about 20 million doses might be available.